Figure 5
From: Pharmacokinetics and biodistribution of the cyclin-dependent kinase inhibitor -CR8- in mice
Time–plasma concentration curve after PO and IV CR8 to the mouse. Plasma time concentration curve after the oral administration of 100 mg/kg CR8 where the dashed line is the estimated two compartment model while the open circles are the observed concentrations. The solid line is the estimated one compartment model after the iv administration of 50 mg/kg CR8, while open triangles represent the measured concentrations.