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Table 2 Performance of the CASA (LBMPE1) and previously published FFM prediction equations in the NWAHS and FAMAS cohorts (age 50 years and over) in the combined cohort and by gender

From: Lean body mass: the development and validation of prediction equations in healthy adults

  Mean (SD), kg Mean error (95%CI), kg P-value for mean error R ρ c(95% CI) [C b] 95% limits of agreement RMSE (95% CI), kg
Total (n = 2287)        
LBM DXA 50.62 (10.8)       
Heitmann equation 54.30 (10.7) 3.68 (3.53, 3.83) <0.001 0.940* 0.888 (0.880, 0.896) [0.945] -3.77, 11.1 5.24 (4.97, 5.51)
Janmahasatian equation 54.23 (11.0) 3.61 (3.46, 3.76) <0.001 0.943* 0.884 (0.884, 0.899) [0.946] -3.78, 11.0 5.17 (4.90, 5.44)
Deurenberg equation 50.64 (10.1) 0.02 (-0.14, 0.19) 0.777 0.931* 0.928 (0.923, 0.934) [0.998] -7.89, 7.93 3.95 (3.70, 4.20)
LBM PE1 51.36 (10.6) 0.74 (0.59, 0.89) <0.001 0.942* 0.939 (0.934, 0.944) [0.998] -6.58, 8.06 3.73 (2.48, 4.98)
Men (n = 1436)        
LBM DXA 57.09 (7.50)       
Heitmann equation 60.56 (7.80) 3.46 (3.25. 3.67) <0.001 0.863* 0.782 (0.764, 0.800) [0.906] -11.5, 4.57 5.30 (4.93, 5.67)
Janmahasatian equation 61.18 (6.80) 4.09 (3.89, 4.29) <0.001 0.852* 0.728 (0.707, 0.747) [0.853] -12.0, 3.82 5.69 (5.32, 6.06)
Deurenberg equation 56.76 (6.80) - 0.34 (-0.55, -0.12) 0.002 0.838* 0.834 (0.818, 0.848) [0.995] -7.92, 8.60 4.14 (3.85, 4.43)
LBM PE1 58.22 (6.11) 1.12 (0.92, 1.33) <0.001 0.851* 0.822 (0.806, 0.837) [0.851] -6.78, 9.02 4.11 (3.80, 4.42)
Women (n = 851)        
LBM DXA 39.70 (5.30)       
Heitmann equation 43.74 (5.55) 4.04 (3.83, 4.26) <0.001 0.833* 0.651 (0.620, 0.680) [0.782] -10.3, 2.26 5.12 (4.75, 5.49)
Janmahasatian equation 42.50 (5.39) 2.81 (2.60, 3.01) <0.001 0.837* 0.722 (0.693, 0.749) [0.872] -8.91, 3.29 4.14 (3.83, 4.45)
Deurenberg equation 40.32 (4.90) 0.63 (0.39, 0.87) <0.001 0.759* 0.751 (0.721, 0.779) [0.990] -7.75, 6.49 3.61 (3.29, 3.93)
LBM PE1 39.78 (5.11) 0.08 (-0.12, 0.28) 0.433 0.835* 0.835 (0.813, 0.854) [0.999] -5.91, 6.07 2.99 (2.74, 3.24)
  1. Mean Error = DXA-PE; LBM, Lean Body Mass; DXA, Dual X-ray absorptiometry; RMSE, Root Mean Square Error; CI, Confidence interval; SD, Standard Deviation; R, Pearson Correlation; Cb = Bias Correction Factor; ρc = Concordance Correlation Coefficient; *p-value <0.001.