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Table 3 Performance of the CASA (LBMPE1) and previously published FFM prediction equations in the NWAHS and FAMAS cohorts (age 50 years and over) across various age groupings

From: Lean body mass: the development and validation of prediction equations in healthy adults

  Mean (SD), kg Mean error (95%CI), kg P-value for mean error R ρ c(95% CI) [C b] 95% limits of agreement RMSE (95% CI), kg
Age 50–64, years (n = 1265)        
LBM DXA 52.27 (11.2)       
Heitmann equation 56.47 (10.8) 4.20 (3.99, 4.40) <0.001 0.944* 0.879 (0.868, 0.890) [0.932] -11.6, 3.23 5.60 (5.26, 5.95)
Janmahasatian equation 55.62 (11.2) 3.35 (3.15, 3.55) <0.001 0.948* 0.907 (0.897, 0.915) [0.956] -10.6, 3.85 4.92 (4.61, 5.23)
Deurenberg equation 53.15 (10.0) 0.87 (0.66, 1.09) <0.001 0.938* 0.929 (0.921, 0.936) [0.990] -8.72, 6.98 4.02 (3.73, 4.31)
LBM PE1 52.77 (10.7) 0.50 (0.30, 0.70) <0.001 0.948* 0.946 (0.939, 0.951) [0.998] -6.68, 7.68 3.62 (3.36, 3.88)
Age 65–79, years (n = 882)        
LBM DXA 49.09 (9.91)       
Heitmann equation 52.23 (10.0) 3.14 (2.90, 3.38) <0.001 0.933* 0.887 (0.873, 0.899) [0.951] -10.5, 4.18 4.82 (4.35, 5.29)
Janmahasatian equation 53.03 (10.5) 3.93 (3.69, 4.18) <0.001 0.933* 0.862 (0.846, 0.876) [0.925] -11.5, 3.66 5.46 (4.97, 5.95)
Deurenberg equation 48.19 (9.14) -0.90 (-1.15, -0.65) <0.001 0.924* 0.916 (0.905, 0.926) [0.993] -6.70, 8.50 3.90 (3.45, 4.35)
LBM PE1 50.20 (10.2) 0.98 (0.73, 1.22) <0.001 0.929* 0.925 (0.915, 0.934) [0.995] -6.57, 8.53 3.90 (3.48, 4.32)
Age ≥80, years (n = 140)        
LBM DXA 44.48 (8.64)       
Heitmann equation 46.71 (9.20) 2.23 (1.60, 2.85) <0.001 0.929* 0.902 (0.868, 0.928) [0.969] -9.05, 4.59 4.06 (3.20, 4.92)
Janmahasatian equation 48.46 (10.1) 3.97 (3.29, 4.66) <0.001 0.936* 0.850 (0.806, 0.883) [0.906] -11.4, 3.46 5.43 (4.31, 6.55)
Deurenberg equation 42.46 (8.41) -2.03 (-2.58, -1.48) <0.001 0.937* 0.911 (0.880, 0.934) [0.971] -3.97, 8.03 3.61 (2.85, 4.37)
LBM PE1 45.84 (9.81) 1.36 (0.80, 1.93) <0.001 0.941* 0.923 (0.897, 0.943) [0.981] -5.39, 8.11 3.63 (2.90, 4.36)
  1. Mean Error = DXA-PE; LBM, Lean Body Mass; DXA, Dual X-ray absorptiometry; RMSE, Root Mean Square Error; CI, Confidence interval; SD, Standard Deviation; R, Pearson Correlation; Cb = Bias Correction Factor; ρc = Concordance Correlation Coefficient; *p-value <0.001.