Figure 2From: Rehabilitating drug-induced long-QT promoters: In-silico design of hERG-neutral cisapride analogues with retained pharmacological activity The group definition of cisapride (i.e., R1 = -C 6 H 4 -F; R2 = -O-CH 2 -; R3 = -CH 2 -CH 2 -; R4 = -C 5 H 3 N-O-CH 3 ; R5 = -NH-CO-; R6 = C 6 H 2 -Cl-NH 2 ; R7 = -O-CH 3 ) for per-group decomposition and inter-monomer contacts from the MM/GBSA analysis. Back to article page