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Table 1 Physiological results from pressure regulated perfusion

From: Diazoxide protects against doxorubicin-induced cardiotoxicity in the rat

  DIADOX DIA5HDDOX 5HDDOX DIASAL 5HDSAL SALSAL SALDOX
LVDP (mmHg) 136.6 ± 2.9* 122.9 ± 4.4 117.5 ± 5.2 146.4 ± 6.8* 144.6 ± 5.1* 152.7 ± 11.0* 120.4 ± 3.6
LVEDP (mmHg) 9.3 ± 1.5* 16.1 ± 1.8 14.9 ± 2.7 8.2 ± 1.5* 8.1 ± 1.6* 8.3. ± 1.6* 15.4 ± 2.2
AoP (mmHg) 73.0 ± 0 73.0 ± 0 73.0 ± 0 73.0 ± 0 73.0 ± 0 73.0 ± 0 73.0 ± 0
Heart rate (beats per minute) 300 ± 0 300 ± 0 300 ± 0 300 ± 0 300 ± 0 300 ± 0 300 ± 0
dp/dtmax (mmHg/s) 3525.5 ± 949.9 3295.3 ± 895.9 3283.4 ± 621.9 3647.4 ± 563.7 3522.5 ± 120.1 4499.1 ± 887.2 3026.6 ± 150.0
dp/dtmin (mmHg/s) −2176.5 ± 1147.9 −2012.3 ± 282.3 −1952.7 ± 373.9 −2921.9 ± 200.3 −3050.9 ± 277.6 −3060.1 ± 311.3 −2173.0 ± 195.1
Coronary flow (ml/min) 11.3 ± 1.8* 9.5 ± 0.7 8.8 ± 1.2 11.8 ± 1.2* 12.0 ± 1.3* 12.6 ± 0.4* 8.9 ± 1.7
  1. Values presented as mean ± standard deviation (SD). *Significantly different from hearts in SALDOX, p < 0.05.