Table 3 Biochemical results and drug analysis
From: Diazoxide protects against doxorubicin-induced cardiotoxicity in the rat
DIADOX | DIA5HDDOX | 5HDDOX | DIASAL | 5HDSAL | SALSAL | SALDOX | |
|---|---|---|---|---|---|---|---|
Troponin -T effluate concentration ng/L | 67.3 ± 7.9* | 126.3 ± 20.5 | 130.0 ± 16.9 | 27.0 ± 4.9* | 26.8 ± 4.9* | 28.0 ± 5.3* | 121.0 ± 17.2 |
H2O2 effluate concentration (μM) | 54.9 ± 2.6* | 72.8 ± 9.2 | 70.6 ± 5.7 | 24.8 ± 3.0* | 26.1 ± 2.5* | 22.8 ± 1.7* | 73.5 ± 2.4 |
Doxorubicin tissue concentration nmol/g | 1.9 ± 0.3 | 2.7 ± 0.4 | 3.3 ± 1.8 | 0 ± 0 | 0 ± 0 | 0 ± 0 | 2.6 ± 0.5 |
Doxorubicinol tissue concentration nmol/g | 0.4 ± 0 | 0.7 ± 0.3 | 0.4 ± 0.1 | 0 ± 0 | 0 ± 0 | 0 ± 0 | 0.5 ± 0.2 |