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Table 2 Distribution of major reasons and documented ADRs responsible for treatment change (based on chart review), ART clinic, Gondar University Hospital, June 2012

From: Self-reported adverse drug reactions and their influence on highly active antiretroviral therapy in HIV infected patients: a cross sectional study

Variables n (%)*
Reasons for treatment change (N = 78)  
  Due to ADRs 62 (79.0) **
  Due to treatment failure 10 (13.0)
  Due to TB co-morbidity 4 (5.0)
  Due to pregnancy 2 (3.0)
Documented ADRs responsible for treatment change (N = 62)
  CNS symptoms 17 (27.4)
  Anemia 10 (16.1)
  Peripheral neuropathy 9(14.5)
  Skin rash 8 (12.9)
  Lipodystrophy 7(11.3)
  Weight loss 4(6.5)
  Stomach ache 3 (4.8)
  Hepatotoxicity 3 (4.8)
  Dental illness 1 (1.6)
  1. *Percent frequency out of the total number of patients (reasons for treatment change, N = 78; ADRs responsible for treatment change, N = 62). The most frequent reasons are highlighted in bold type.
  2. **95% CI, 0.68-0.88; p =0.00.