|
Variables
|
n (%)*
|
|---|
|
Reasons for treatment change (N = 78)
| |
|
Due to ADRs
|
62 (79.0)
**
|
|
Due to treatment failure
|
10 (13.0)
|
|
Due to TB co-morbidity
|
4 (5.0)
|
|
Due to pregnancy
|
2 (3.0)
|
|
Documented ADRs responsible for treatment change (N = 62)
|
|
CNS symptoms
|
17 (27.4)
|
|
Anemia
|
10 (16.1)
|
|
Peripheral neuropathy
|
9(14.5)
|
|
Skin rash
|
8 (12.9)
|
|
Lipodystrophy
|
7(11.3)
|
|
Weight loss
|
4(6.5)
|
|
Stomach ache
|
3 (4.8)
|
|
Hepatotoxicity
|
3 (4.8)
|
|
Dental illness
|
1 (1.6)
|
-
*Percent frequency out of the total number of patients (reasons for treatment change, N = 78; ADRs responsible for treatment change, N = 62). The most frequent reasons are highlighted in bold type.
-
**95% CI, 0.68-0.88; p =0.00.
