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Table 1 An example of the chemotherapy hydration regimen for each group

From: Magnesium supplementation and high volume hydration reduce the renal toxicity caused by cisplatin-based chemotherapy in patients with lung cancer: a toxicity study

   High-volume hydration Mg- High-volume hydration Mg+ Low-volume hydration Mg+
    ml   ml   ml
Day 1   N.S. 50 N.S. 50 N.S. 50
  Antiemetics      N.S. 100
   Granisetoron 3 mg 100 Granisetoron 3 mg 100 Fosaprepitant meglumine 150 mg  
   Dexamethasone 6.6 mg 2 Dexamethasone 6.6 mg 2 N.S. 50
       Palonosetoron 0.75 mg 5
       Dexamethasone 9.9 mg 2
  Other cytotoxic agent N.S. with other cytotoxic agent 500 N.S. with other cytotoxic agent 500 N.S. with other cytotoxic agent 100
  Pre-hydration N.S. 500 N.S. 500 1/4 saline solution 500
   1/4 saline solution 500 1/4 saline solution 500 MgSO4 8 mEq  
     MgSO4 8 mEq    
  Diuresis    20% Mannitol 300 20% Mannitol 300
  Cisplatin N.S. with cisplatin 300 N.S. with cisplatin 300 N.S. with cisplatin 100
  Post-hydration N.S. 500 N.S. 500 N.S. 500
  Diuresis 20% Mannitol 300     
  Post-hydration 1/4 saline solution 500 1/4 saline solution 500 1/4 saline solution 500
  Diuresis 20% Mannitol 300 20% Mannitol 300   
   Frosemide 20 mg 2 Frosemide 20 mg 2   
  Oral hydration   0   0   2,000
Day 2,3   N.S. 50 N.S. 50   
  Antiemetics Granisetoron 3 mg 100 Granisetoron 3 mg 100   
   Dexamethasone 6.6 mg 2 Dexamethasone 6.6 mg 2   
  Hydration 1/4 saline solution 500 1/4 saline solution 500   
  Diuresis 20% Mannitol 300 20% Mannitol 300   
  Oral hydration   0   0   1,000
  Total infusion Day 1 3,550 Day 1 3,550 Day 1 2,200
   Day 2,3 950 Day 2,3 950 Day 2,3 0
  1. N.S., normal saline.