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Figure 1 | BMC Pharmacology and Toxicology

Figure 1

From: Population pharmacokinetic and pharmacodynamic modeling of transformed binary effect data of triflusal in healthy Korean male volunteers: a randomized, open-label, multiple dose, crossover study

Figure 1

PK and PD study designs. Subjects (n = 34) eligible for this study were given a 900 mg loading dose on day 1, followed by a 600 mg/day maintenance dose on days 2, 3, 5, 7, 8, and 9. For PK assessment, blood samples were obtained at time 0, 24, 48, 96, 144, 168, 192, 192.5, 193, 194, 196, 199, 202 and 216 h. For PD assessment, blood samples were obtained at time 0, 24, 48, 96, 144, 168, 192, 196, 202, and 216 h. PK, pharmacokinetic; PD, pharmacodynamic; IPA, inhibition of platelet aggregation.

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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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