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Table 2 Approach of i.v. to oral antibacterial switch therapy

From: An outpatient antibacterial stewardship intervention during the journey to JCI accreditation

i.v. antibacterials Oral antibacterials Daily expenditure ratio (oral to i.v.)
Fluoroquinolones   
i.v. moxifloxacin Moxifloxacin tablets 0.10
i.v. levofloxacin Levofloxacin tablets 0.13
Cephalosporins   
The first generation   
i.v. cefathiamidine Cefradine capsules 0.056
The second generation cephalosporins and macrolides 0.041-0.14 (median: 0.078)
The second generation   
i.v. cefotiam Cefaclor capsules 0.092
i.v. cefuroxime sodium Cefaclor SR tablets 0.99
  Cefprozi tablets 0.15
  Cefuroxime axetil tablets 0.061
The third generation   
i.v. ceftizoxime sodium Cefdinir capsules 0.35
i.v. ceftriaxone sodium Cefetamet pivoxil tablets 0.042
Macrolides   
i.v. azithromycin Azithromycin tablets 0.29
  Roxithromycin tablets 0.13
  Clarithromycin SR tablets 0.088
  Clarithromycin tablets 0.21
Aminoglycosides   
i.v. etimicin Levofloxacin tablets 0.097
  Cefdinir capsules 0.34
  Cefetamet pivoxil tablets 0.090
Nitroimidazoles   
i.v. ornidazole Ornidazole tablets 0.017
Lincosamide   
i.v. clindamycin Clindamycin palmitate tablets 1.11
  1. Daily expenditure was expressed in Chinese Yuan Renminbi (CNY); i.v.: intravenous; SR: sustained release. Daily expenditure ratio (oral to i.v.) was calculated as daily expenditure of oral antibacterial divided by daily expenditure of the corresponding i.v. antibacterial.