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Table 2 Prevalence of use of different antihypertensive drug classes in patients treated with one, two or three or more antihypertensive drugs

From: Utilization of antihypertensive drugs in obesity-related hypertension: a retrospective observational study in a cohort of patients from Southern Italy

Whole patient cohort

Patients not taking antidiabetic and/or lipid lowering drugs

Patients treated with a single antihypertensive drug

 

All patients

Male

Female

All patients

Male

Female

 

(n = 53; 50.0 ± 10.4 yr)

(n = 16; 49.6 ± 10.9 yr)

(n = 37; 50.2 ± 10.3 yr)

(n = 45; 50.0 ± 10.4 yr)

(n = 11; 48.3 ± 12.2 yr)

(n = 34; 50.2 ± 11.3 yr)

β-blockers

15 (28.3)

1 (6.3)

14 (37.8)*

12 (26.7)

------

12 (35.3)*

ACEIs

15 (28.3)

8 (50.0)

7 (18.9)*

13 (28.9)

6 (54.5)

7 (20.6)*

ARBs

13 (24.5)

5 (31.3)

8 (21.6)

12 (26.7)

4 (36.4)

8 (23.5)

CCBs

7 (13.2)

2 (12.5)

5 (13.5)

6 (13.3)

1 (9.1)

5 (14.7)

Diuretics

1 (1.9)

------

1 (2.7)

1 (2.2)

------

1 (2.9)

α1 adrenergic blockers

2 (3.8)

------

2 (5.4)

1 (2.2)

------

1 (2.9)

Patients treated with two antihypertensive drugs

 

All patients

Male

Female

All patients

Male

Female

 

(n = 47; 53.1 ± 9.5 yr)

(n = 15; 51.7 ± 8.3 yr)

(n = 32; 53.8 ± 10.1 yr)

(n = 38; 52.0 ± 8.7 yr)

(n = 10; 49.9 ± 9.1yr)

(n = 28; 52.8 ± 8.7 yr)

β-blockers

12 (25.5)

3 (20.0)

10 (31.3)

10 (26.3)

1 (10.0)

9 (32.1)

ACEIs

19 (40.4)

9 (60.0)

10 (31.3)

14 (36.8)

7 (70.0)

7 (25.0)*

ARBs

23 (48.9)

5 (33.3)

18 (56.3)

19 (50.0)

3 (30.0)

16 (57.1)

CCBs

8 (17.0)

1 (6.7)

7 (21.9)

6 (15.8)

1 (10.0)

5 (17.9)

Diuretics

30 (63.8)

11 (73.3)

19 (59.4)

26 (68.4)

8 (80.0)

18 (64.3)

α1 adrenergic blockers

1 (2.1)

------

1 (3.1)

-------

-------

-------

Patients treated with three or more antihypertensive drugs

 

All patients

Male

Female

All patients

Male

Female

 

(n = 29; 53.6 ± 10.4 yr)

(n = 15; 52.9 ± 9.6 yr)

(n = 14; 54.4 ± 11.5 yr)

(n = 21; 51.3 ± 9.6 yr)

(n = 9; 50.1 ± 9.8 yr)

(n = 12; 52.3 ± 9.8 yr)

β-blockers

18 (62.1)

9 (60.0)

9 (64.3)

12 (57.1)

4 (44.4)

8 (66.7)

ACEIs

6 (20.7)

2 (13.3)

4 (28.6)

6 (28.6)

2 (22.2)

4 (33.3)

ARBs

19 (65.5)

10 (66.7)

9 (64.3)

14 (66.7)

6 (66.7)

8 (61.5)

CCBs

10 (34.5)

9 (60.0)

1 (7.1)**

8 (38.1)

7 (77.8)

1 (8.3)

Diuretics

28 (96.6)

14 (93.3)

14 (100)

21 (100)

9 (100)

12 (100)

α1 adrenergic blockers

4 (13.8)

2 (13.3)

2 (14.3)

3 (14.3)

1 (11.1)

2 (16.7)

  1. The numbers in parentheses represent the percentage of the total of the respective group
  2. *p < 0.05 vs males
  3. **p < 0.01 at χ2 test