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Table 2 Prevalence of use of different antihypertensive drug classes in patients treated with one, two or three or more antihypertensive drugs

From: Utilization of antihypertensive drugs in obesity-related hypertension: a retrospective observational study in a cohort of patients from Southern Italy

Whole patient cohort Patients not taking antidiabetic and/or lipid lowering drugs
Patients treated with a single antihypertensive drug
  All patients Male Female All patients Male Female
  (n = 53; 50.0 ± 10.4 yr) (n = 16; 49.6 ± 10.9 yr) (n = 37; 50.2 ± 10.3 yr) (n = 45; 50.0 ± 10.4 yr) (n = 11; 48.3 ± 12.2 yr) (n = 34; 50.2 ± 11.3 yr)
β-blockers 15 (28.3) 1 (6.3) 14 (37.8)* 12 (26.7) ------ 12 (35.3)*
ACEIs 15 (28.3) 8 (50.0) 7 (18.9)* 13 (28.9) 6 (54.5) 7 (20.6)*
ARBs 13 (24.5) 5 (31.3) 8 (21.6) 12 (26.7) 4 (36.4) 8 (23.5)
CCBs 7 (13.2) 2 (12.5) 5 (13.5) 6 (13.3) 1 (9.1) 5 (14.7)
Diuretics 1 (1.9) ------ 1 (2.7) 1 (2.2) ------ 1 (2.9)
α1 adrenergic blockers 2 (3.8) ------ 2 (5.4) 1 (2.2) ------ 1 (2.9)
Patients treated with two antihypertensive drugs
  All patients Male Female All patients Male Female
  (n = 47; 53.1 ± 9.5 yr) (n = 15; 51.7 ± 8.3 yr) (n = 32; 53.8 ± 10.1 yr) (n = 38; 52.0 ± 8.7 yr) (n = 10; 49.9 ± 9.1yr) (n = 28; 52.8 ± 8.7 yr)
β-blockers 12 (25.5) 3 (20.0) 10 (31.3) 10 (26.3) 1 (10.0) 9 (32.1)
ACEIs 19 (40.4) 9 (60.0) 10 (31.3) 14 (36.8) 7 (70.0) 7 (25.0)*
ARBs 23 (48.9) 5 (33.3) 18 (56.3) 19 (50.0) 3 (30.0) 16 (57.1)
CCBs 8 (17.0) 1 (6.7) 7 (21.9) 6 (15.8) 1 (10.0) 5 (17.9)
Diuretics 30 (63.8) 11 (73.3) 19 (59.4) 26 (68.4) 8 (80.0) 18 (64.3)
α1 adrenergic blockers 1 (2.1) ------ 1 (3.1) ------- ------- -------
Patients treated with three or more antihypertensive drugs
  All patients Male Female All patients Male Female
  (n = 29; 53.6 ± 10.4 yr) (n = 15; 52.9 ± 9.6 yr) (n = 14; 54.4 ± 11.5 yr) (n = 21; 51.3 ± 9.6 yr) (n = 9; 50.1 ± 9.8 yr) (n = 12; 52.3 ± 9.8 yr)
β-blockers 18 (62.1) 9 (60.0) 9 (64.3) 12 (57.1) 4 (44.4) 8 (66.7)
ACEIs 6 (20.7) 2 (13.3) 4 (28.6) 6 (28.6) 2 (22.2) 4 (33.3)
ARBs 19 (65.5) 10 (66.7) 9 (64.3) 14 (66.7) 6 (66.7) 8 (61.5)
CCBs 10 (34.5) 9 (60.0) 1 (7.1)** 8 (38.1) 7 (77.8) 1 (8.3)
Diuretics 28 (96.6) 14 (93.3) 14 (100) 21 (100) 9 (100) 12 (100)
α1 adrenergic blockers 4 (13.8) 2 (13.3) 2 (14.3) 3 (14.3) 1 (11.1) 2 (16.7)
  1. The numbers in parentheses represent the percentage of the total of the respective group
  2. *p < 0.05 vs males
  3. **p < 0.01 at χ2 test