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Table 2 Opioid adverse effect codes used in combination with related diagnostic codes used to identify overdoses. To meet criteria, a case had to include one diagnosis from category A and one more diagnoses from category B on the same date

From: Protocol: changes in rates of opioid overdose and poisoning events in an integrated health system following the introduction of a formulation of OxyContin® with abuse-deterrent properties

Diagnostic category Diagnosis ICD 9 code ICD 10 code HCPCS code
A Adverse effects of heroin E935.0   
A Adverse effects of methadone E935.1   
A Adverse effects of other opioids and related narcotics E935.2   
A COD: Adverse effects of opioids and related analgesics   Y45.0  
B Mixed acid–base balance disorder 276.4   
B Drug-induced psychotic disordersa 292.1   
B Drug-induced delirium 292.81   
B Drug-induced mental disorderb 292.8   
B Pneumonia, organism unspecified 486   
B Chronic airway obstruction, not elsewhere classified 496   
B Acute respiratory failure 518.81   
B Other pulmonary insufficiency, not elsewhere classified 518.82   
B Rhabdomyolysis 728.88   
B Alteration of consciousness 780.0   
B Altered mental state 780.97   
B Apnea 786.03   
B Shortness of breath 786.05   
B Dyspnea and respiratory abnormalities—other 786.09   
B Painful respiration 786.52   
B Asphyxia and hypoxemia 799.0   
B Poisoning by opiate antagonists 970.1   
B Suicide and self-inflicted injury E950–E959   
B Assault by drugs and medicinal substances E962.0   
B Injection, Naloxone Hydrochloride    J2310
  1. a Including 292.11 and 292.12
  2. b Excluding 292.81