Role of phenolics from Spondias pinnata bark in amelioration of iron overload induced hepatic damage in Swiss albino mice

Table 1 The effect of GA and MG on serum marker enzymes (ALAT, ASAT and ALP) and Bilirubin in iron overloaded mice

Treatment	ALAT (Unit/L)		ASAT (Unit/L)		ALP (Unit/L)		Bilirubin (mg/dl)
Treatment	GA	MG	GA	MG	GA	MG	GA	MG
B	14.42 ± 1.91	14.42 ± 1.91	62.46 ± 6.32	62.46 ± 6.32	84.62 ± 3.48	84.62 ± 3.48	1.58 ± 0.10	1.58 ± 0.10
C	64.60 ± 4.32 ^X3	64.60 ± 4.32 ^X3	234.91 ± 8.30 ^X3	234.91 ± 8.30 ^X3	252.63 ± 4.92 ^X3	252.63 ± 4.92 ^X3	3.15 ± 0.18 ^X3	3.15 ± 0.18 ^X3
2 mg/kg b.w	42.96 ± 1.16 ^X3Y3	36.93 ± 0.93 ^X3Y3	145.45 ± 5.89 ^X3Y3	141.51 ± 11.57^X3Y3	181.90 ± 4.95 ^X3Y3	173.41 ± 2.93 ^X3Y3	2.88 ± 0.39 ^X3	3.04 ± 0.25 ^X3
4 mg/kg b.w	32.17 ± 2.16 ^X3Y3	29.09 ± 0.59 ^X3Y3	114.78 ± 8.20 ^X3Y3	110.28 ± 6.55 ^X3Y3	145.10 ± 6.46 ^X3Y3	132.32 ± 3.56 ^X3Y3	2.47 ± 0.24 ^X3Y3	2.11 ± 0.16 ^X3Y3
8 mg/kg b.w	23.22 ± 0.95 ^X3Y3	20.25 ± 0.90 ^X2Y3	83.56 ± 4.86 ^X3Y3	77.93 ± 13.48 ^X1Y3	118.69 ± 3.79 ^X3Y3	103.34 ± 5.88 ^X3Y3	2.10 ± 0.12 ^X3Y3	1.94 ± 0.13 ^X3Y3
D	19.85 ± 0.79 ^X3Y3	19.85 ± 0.79 ^X3Y3	88.06 ± 10.37 ^X3Y3	88.06 ± 10.37 ^X3Y3	114.97 ± 6.13 ^X3Y3	114.97 ± 6.13 ^X3Y3	1.72 ± 0.14 ^Y3	1.72 ± 0.14 ^Y3

Values are mean ± SD of six observations. Treatment groups are B: Normal mice; C: Iron-dextran treated mice receiving normal saline; 2 mg/kg b.w. treated group; 4 mg/kg b.w. treated group; 8 mg/kg b.w. treated group; D: 20 mg/kg b.w. desirox treated group. X1: p < 0.05, X2: p < 0.01 and X3: p < 0.001 significant difference from normal mice (B) group. Y1: p < 0.05, Y2: p < 0.01 and Y3: p < 0.001 significant difference from iron overloaded (C) group

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