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Table 1 The effect of GA and MG on serum marker enzymes (ALAT, ASAT and ALP) and Bilirubin in iron overloaded mice

From: Role of phenolics from Spondias pinnata bark in amelioration of iron overload induced hepatic damage in Swiss albino mice

Treatment ALAT (Unit/L) ASAT (Unit/L) ALP (Unit/L) Bilirubin (mg/dl)
GA MG GA MG GA MG GA MG
B 14.42 ± 1.91 14.42 ± 1.91 62.46 ± 6.32 62.46 ± 6.32 84.62 ± 3.48 84.62 ± 3.48 1.58 ± 0.10 1.58 ± 0.10
C 64.60 ± 4.32 X3 64.60 ± 4.32 X3 234.91 ± 8.30 X3 234.91 ± 8.30 X3 252.63 ± 4.92 X3 252.63 ± 4.92 X3 3.15 ± 0.18 X3 3.15 ± 0.18 X3
2 mg/kg b.w 42.96 ± 1.16 X3Y3 36.93 ± 0.93 X3Y3 145.45 ± 5.89 X3Y3 141.51 ± 11.57X3Y3 181.90 ± 4.95 X3Y3 173.41 ± 2.93 X3Y3 2.88 ± 0.39 X3 3.04 ± 0.25 X3
4 mg/kg b.w 32.17 ± 2.16 X3Y3 29.09 ± 0.59 X3Y3 114.78 ± 8.20 X3Y3 110.28 ± 6.55 X3Y3 145.10 ± 6.46 X3Y3 132.32 ± 3.56 X3Y3 2.47 ± 0.24 X3Y3 2.11 ± 0.16 X3Y3
8 mg/kg b.w 23.22 ± 0.95 X3Y3 20.25 ± 0.90 X2Y3 83.56 ± 4.86 X3Y3 77.93 ± 13.48 X1Y3 118.69 ± 3.79 X3Y3 103.34 ± 5.88 X3Y3 2.10 ± 0.12 X3Y3 1.94 ± 0.13 X3Y3
D 19.85 ± 0.79 X3Y3 19.85 ± 0.79 X3Y3 88.06 ± 10.37 X3Y3 88.06 ± 10.37 X3Y3 114.97 ± 6.13 X3Y3 114.97 ± 6.13 X3Y3 1.72 ± 0.14 Y3 1.72 ± 0.14 Y3
  1. Values are mean ± SD of six observations. Treatment groups are B: Normal mice; C: Iron-dextran treated mice receiving normal saline; 2 mg/kg b.w. treated group; 4 mg/kg b.w. treated group; 8 mg/kg b.w. treated group; D: 20 mg/kg b.w. desirox treated group. X1: p < 0.05, X2: p < 0.01 and X3: p < 0.001 significant difference from normal mice (B) group. Y1: p < 0.05, Y2: p < 0.01 and Y3: p < 0.001 significant difference from iron overloaded (C) group