Table 6 Mean individual pharmacodynamic parameters and confidence intervals for IFNs alpha-2b and gamma

 S_max

25.8

25.2–26.4

16.7

15.8–17.6

 SC₅₀ (pg/mL)

15.5

14.8–16.1

19.5

13.8–25.3

 k_in (h⁻¹)

0.027

0.024–0.030

0.03

0.026–0.034

 k_out (h⁻¹)

0.022

0.022–0.022

0.0247

0.0247–0.0248

 S_max

1.03

0.95–1.1

4.5

3.81–5.1

 SC₅₀ (pg/mL)

0.31

0.03–0.58

76.4

37.2–115.7

 k_in (h⁻¹)

0.141

0.133–0.149

0.04

0.033–0.038

 k_out (h⁻¹)

0.070

0.067–0.073

0.0194

0.0190–0.0198

 S₀ (ng/mL)

33.9

14.5–53.3

762

721–803

 S_max

25.8

10.6–41.0

104

39–169

 SC₅₀ (pg/mL)

419

392–446

730

394–1066

 k_in (h⁻¹)

1990

1754–2226

237

188–285

 k_out (h⁻¹)

28.20

14.21–42.18

17.7

6.2–29.1

 S₀ (°C)

35.9

35.9–35.9

36.2

36.0–36.2

 S_max

9.7

9.5–9.8

7.2

6.7–7.6

 SC₅₀ (pg/mL)

252

239–264

374

254–493

 k_in (h⁻¹)

0.864

0.858–0.870

0.851

0.848–0.855

 k_out (h⁻¹)

1.0155

1.015–1.016

1.021

1.021–1.021