Fig. 4

Induction of ROS in MCF-7 cells after treatment with plumbagin (4), rapanone (9), and doxorubicin for 24 h. IC₅₀ values were 0.06 μM (4), 16.94 (9) and 0.35 μM (doxorubicin). Cells were treated with ¼ × IC₅₀ (C1), ½ × IC₅₀ (C2) and IC₅₀ (C3) of each compound