Table 4 Effect of the subchronic 13-week oral administration of POM93 on hematological parameters in Wistar rats
From: Genotoxicity and acute and subchronic toxicity studies of a bioactive polyoxometalate in Wistar rats
Time (d) | Hematological parameters | POM93 (mg/kg) | |||
|---|---|---|---|---|---|
Control water | 62.2 | 195.7 | 587.0 | ||
90 | WBC (× 109/L) | 14.20 ± 5.07 | 9.40 ± 2.91 | 12.20 ± 3.52 | 13.44 ± 4.33 |
RBC (× 1012/L) | 9.11 ± 0.77 | 8.28 ± 1.16 | 8.67 ± 0.73 | 8.79 ± 1.91 | |
PLT (× 109/L) | 657.40 ± 402.57 | 334.20 ± 296.94 | 356.40 ± 247.47 | 536.56 ± 338.81 | |
HB (g/L) | 149.60 ± 11.88 | 142.50 ± 19.42 | 147.50 ± 15.36 | 144.67 ± 20.43 | |
105 | WBC (× 109/L) | 15.36 ± 3.45 | 15.52 ± 4.18 | 16.90 ± 12.35 | 24.20 ± 10.20 |
RBC (× 1012/L) | 8.96 ± 1.00 | 8.77 ± 0.91 | 8.72 ± 0.90 | 8.44 ± 0.81 | |
PLT (× 109/L) | 500.56 ± 185.23 | 490.90 ± 260.25 | 519.90 ± 343.95 | 587.67 ± 366.49 | |
HB (g/L) | 149.56 ± 13.91 | 152.20 ± 12.93 | 143.90 ± 12.41 | 135.17 ± 16.38 | |