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Fig. 8 | BMC Pharmacology and Toxicology

Fig. 8

From: Salidroside contributes to reducing blood pressure and alleviating cerebrovascular contractile activity in diabetic Goto-Kakizaki Rats by inhibition of L-type calcium channel in smooth muscle cells

Fig. 8

Treatment with SAL for 48 h inhibited the mRNA expressions of CaL α1C-subunit and MLCK in cultured cerebral VSMCs under high glucose condition. Relative mRNA levels of CaL α1C-subunit (a) and MLCK (b) are shown as a percentage of the β-actin mRNA, respectively. It is shown the relative mRNA levels of CaL α1C-subunit (c) in cultured cerebral VSMCs under normal glucose condition. Values are expressed as means ± SEM from 4 independent experiments. *P ≤ 0.05 as compared with high glucose control and #P < 0.05 vs. treatment with SAL treatment

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