From: Modulation of hepatic perfusion did not improve recovery from hepatic outflow obstruction
 | 0 h pre-OP | 0 h post-OP | 24 h post-OP | ||||||
---|---|---|---|---|---|---|---|---|---|
PVP [mmHg] | PVF [ml/min · g] | HAF [ml/min · g] | PVP [mmHg] | PVF [ml/min · g] | HAF [ml/min · g] | PVP [mmHg] | PVF [ml/min · g] | HAF [ml/min · g] | |
Saline | 12,2 ± 2,4 | 1,3 ± 0,2 | 0,2 ± 0,0 | 15,4 ± 4,4 | 1,2 ± 0,4 | 0,2 ± 0,1 | 12,3 ± 2,7 | 3,3 ± 0,5 | 0,01 ± 0,0 |
Splenectomy | 12,2 ± 2,4 | 1,3 ± 0,2 | 0,2 ± 0,0 | 14,3 ± 4,4 | 0,9 ± 0,2* | 0,1 ± 0,1 | 11,0 ± 1,3 | 2,9 ± 1,0 | 0,02 ± 0,0 |
Carvedilol | 8,4 ± 0,3* | 1,4 ± 0,2 | 0,2 ± 0,1 | 12,0 ± 0,6 | 1,3 ± 0,1 | 0,2 ± 0,0 | 11,2 ± 1,8 | 4,3 ± 1,1 | 0,02 ± 0,0 |
Isosorbide-5-mononitrate | 7,4 ± 1,8* | 1,4 ± 0,1 | 0,3 ± 0,1 | 9,6 ± 2,3 | 1,2 ± 0,4 | 0,2 ± 0,1 | 10,6 ± 2,9 | 3,7 ± 1,7 | 0,06 ± 0,1 |
Sildenafil | - | - | - | - | - | - | 11,8 ± 2,3 | 4,1 ± 1,9 | 0,01 ± 0,0 |
Terlipressin | - | - | - | - | - | - | 12,8 ± 1,2 | 4,0 ± 1,5 | 0,03 ± 0,0 |
Octreotide | - | - | - | - | - | - | 9,9 ± 2,3 | 3,7 ± 0,7 | 0,03 ± 0,0 |