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Fig. 4 | BMC Pharmacology and Toxicology

Fig. 4

From: Liraglutide modulates GABAergic signaling in rat hippocampal CA3 pyramidal neurons predominantly by presynaptic mechanism

Fig. 4

The mIPSCs are not enhanced by liraglutide when co-applied with TTX. (a) TTX (1 μM) decreased the frequency and amplitude of the IPSCs and the effect was maintained when 100 nM liraglutide was added. No significant increase of sIPSC frequency (b) or amplitude (c) between TTX (•) and TTX + 100 nM (■) liraglutide application (n = 8). Solid and dash lines in (c) indicate cumulative probability histogram of mIPSCs in the presence of TTX before and after application of liraglutide, respectively (n = 8)

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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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