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Table 3 Baseline features of the studies

From: Adverse clinical outcomes associated with double dose clopidogrel compared to the other antiplatelet regimens in patients with coronary artery disease: a systematic review and meta-analysis

Studies Age (years) Males (%) HBP (%) DS (%) DM (%) CS (%)
  DDC/C DDC/C DDC/C DDC/C DDC/C DDC/C
CURRENT OASIS 7 61.2/61.2 76.0/74.9 59.4/58.8 40.3/40.3 22.3/22.2 37.5/36.6
OPTIMUS2007 64.0/59.0 60.0/70.0 90.0/95.0 90.0/95.0 100/100 15.0/20.0
Khatri2013 64.0/62.0 100/8.00 81.0/91.0 100/97.0 73.0/61.0 69.0/61.0
OPTIMUS3 61.3/61.3 68.6/68.6 94.3/94.3 94.3/94.3 100/100 20.0/20.0
PRINCIPLE TIMI 44 63.8/64.0 77.8/71.6 77.8/85.3 86.9/90.2 29.3/32.4 16.2/17.6
Tailor2014 63.0/63.0 82.7/74.1 82.7/74.1 88.5/83.3 34.6/29.6 67.3/77.8
Chen2017 59.8/60.8 62.0/59.6 56.0/56.1 26.0/28.1 30.0/31.6 38.0/35.1
Wu2017 62.7/60.4 70.0/75.0 70.0/50.0 60.0/80.0 30.0/45.0 30.0/55.0
ACCEL AMI 61.1/62.7 76.7/71.7 36.7/46.7 46.7/36.7 20.0/21.7 73.3/61.7
ACCEL DM 62.0/64.0 66.7/70.7 64.1/75.6 33.3/34.1 100/100 43.6/41.5
CREATIVE 58.1/58.5 61.0/59.3 61.0/65.8 68.5/64.5 32.0/33.8 38.2/36.5
Ha2013 62.3/64.9 71.4/67.7 76.1/71.4 42.5/33.3 100/100 23.8/23.8
HOST ASSURE 63.7/62.8 67.0/69.8 68.6/66.8 62.7/64.2 31.3/31.8 30.8/32.8
Jeong2009 63.0/63.0 66.7/66.7 50.0/53.3 20.0/20.0 16.7/30.0 60.0/36.7
  1. Abbreviations: DDC: double dose clopidogrel, C: control group, HBP: high blood pressure, DS: dyslipidemia, DM: diabetes mellitus, CS: current smoker