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Table 3 Baseline features of the studies

From: Adverse clinical outcomes associated with double dose clopidogrel compared to the other antiplatelet regimens in patients with coronary artery disease: a systematic review and meta-analysis

Studies

Age (years)

Males (%)

HBP (%)

DS (%)

DM (%)

CS (%)

 

DDC/C

DDC/C

DDC/C

DDC/C

DDC/C

DDC/C

CURRENT OASIS 7

61.2/61.2

76.0/74.9

59.4/58.8

40.3/40.3

22.3/22.2

37.5/36.6

OPTIMUS2007

64.0/59.0

60.0/70.0

90.0/95.0

90.0/95.0

100/100

15.0/20.0

Khatri2013

64.0/62.0

100/8.00

81.0/91.0

100/97.0

73.0/61.0

69.0/61.0

OPTIMUS3

61.3/61.3

68.6/68.6

94.3/94.3

94.3/94.3

100/100

20.0/20.0

PRINCIPLE TIMI 44

63.8/64.0

77.8/71.6

77.8/85.3

86.9/90.2

29.3/32.4

16.2/17.6

Tailor2014

63.0/63.0

82.7/74.1

82.7/74.1

88.5/83.3

34.6/29.6

67.3/77.8

Chen2017

59.8/60.8

62.0/59.6

56.0/56.1

26.0/28.1

30.0/31.6

38.0/35.1

Wu2017

62.7/60.4

70.0/75.0

70.0/50.0

60.0/80.0

30.0/45.0

30.0/55.0

ACCEL AMI

61.1/62.7

76.7/71.7

36.7/46.7

46.7/36.7

20.0/21.7

73.3/61.7

ACCEL DM

62.0/64.0

66.7/70.7

64.1/75.6

33.3/34.1

100/100

43.6/41.5

CREATIVE

58.1/58.5

61.0/59.3

61.0/65.8

68.5/64.5

32.0/33.8

38.2/36.5

Ha2013

62.3/64.9

71.4/67.7

76.1/71.4

42.5/33.3

100/100

23.8/23.8

HOST ASSURE

63.7/62.8

67.0/69.8

68.6/66.8

62.7/64.2

31.3/31.8

30.8/32.8

Jeong2009

63.0/63.0

66.7/66.7

50.0/53.3

20.0/20.0

16.7/30.0

60.0/36.7

  1. Abbreviations: DDC: double dose clopidogrel, C: control group, HBP: high blood pressure, DS: dyslipidemia, DM: diabetes mellitus, CS: current smoker