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Fig. 3 | BMC Pharmacology and Toxicology

Fig. 3

From: Hesperidin alleviates zinc oxide nanoparticle induced hepatotoxicity and oxidative stress

Fig. 3

Effect of HSP and nZnO on the histology of rat livers: a Control group, showing normal liver architecture showing portal area (circle), hepatic strands of eosinophils (arrow), central vein (CV). b nZnO treated group showing portal tract expansion (square), hyalinization of hepatocytes, and dense infiltration of mononuclear cells (asterisks’), increase of Kupffur cell (kc), accumulation of cells around central vein. c Section of rat liver (HSP treated) showing normal hepatocytes and central vein (CV) similar to control. d Section of rat livers (HSP+ nZnO treated) showing normal cellular appearance and decrease in toxicity (arrow). Scale bar 50 μm. H & E stain

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