Enhancement of saquinavir absorption and accumulation through the formation of solid drug nanoparticles

Table 1 Properties (chemical compositions and sizes) of the SQV SDNs

Sample	% SQV mesylate	% HPMC	% PVP	% PVA	% Pluronic F 127	% Lecithin S 75	% Span 80	Initial sample PS/nm	Type
SQV 05	20	70			10			430
SQV 06	20				10			117	M
SQV 07	20		70		10			100	M
SQV 09	20	65			10	5		196
SQV 13	20			65	10		5	336

HPMC Hydroxypropyl methyl cellulose, PVP Polyvinylpyrrolidone, PVA Polyvinyl alcohol, M Multimodal, PS Particle size

ISSN: 2050-6511