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Table 1 Overview of Nicotine intoxication cases and their toxicological results

From: Near fatal intoxication by nicotine and propylene glycol injection: a case report of an e-liquid poisoning

CASE Route IVa or POb Co intoxication Amout of *-Nicotine use (mg) Time to sample (hours) Plasmatic nicotine level μg/l Plasmatic cotinine level μg/l Clinical findings Issue
Thornton [8] IV Amphetamine 400 x 2000 2100 Cardiac asystoly †
Sommerfeld Case 1 [9] Po none 372 1.5 96 2800 Nausea, vomiting, Hypotension, bradycardia survived
Sommerfeld Case 2 [9] IV Ethanol (70 mg/ml) 128.8 2 800 2400 Coma, bradypnea, nausea survived
Martin kleish [21] Po none 2288.5 2 528 176 Tachycardia, hypertension, myosis, abominal pain survived
Solarino [10] Po Ethanol 2,1 g/l 1000 (in stomach) x 2200 2200 No data †
Our case IV none 1000 18.5 12 3200 tachycardia, coma, bradypnea,mydriasis, myoclonus, flaccid paresia, type 2 NSTEMI survived
  1. aIV: injection
  2. bPo: ingestion
  3. † Death
  4. X time not known
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