Table 2 Histopathological features of the abatacept-treated group
From: Abatacept induced granulomatous hepatitis with a sarcoidosis- like reaction: a blinded trial in mice
Mouse No. | Portal Tract | Liver Lobule |
|---|---|---|
B1 | Granuloma, Eosinophils ++ lymphocytes++, histiocytes+ | Small Granuloma and eosinophils+ Apoptosis |
B2 | Eosinophils+++, lymphocytes ++, histiocytes+ | Small Granuloma and eosinophils++ Apoptosis + Focal EMH+ |
B3 | neutrophils+++, lymphocytes++, histiocytes+ | Small Granuloma and eosinophils++ Apoptosis + |
B4 | Eosinophils+, lymphoctes +, histiocytes+ | Granuloma and eosinophils++ |
B5 | Eosinophils+, lymphoctes +, histiocytes+ | Granuloma+++ and eosinophils++ |
B6 | Normal | Normal |
B7 | lymphocytes+ plasma cells, histiocytes+ | Focal EMH |