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Table 4 Prognostic effects of drugs in CHF patients with and without low GFR

From: Relationship between drug application and mortality rate in Chinese older coronary artery disease/chronic heart failure patients with and without low glomerular filtration rate

DrugsWithout low GFRWith low GFR
Survival time (days)P valueP valueSurvival time (days)P valueP value
No useUseNo useUse
Beta-blockers806 (652–959)774 (686–863)0.6330.866928 (705–1151)603 (492–714)0.7420.885
ACEI/ARBs791 (670–912)805 (697–913)0.3700.911634 (461–808)702 (556–847)0.1250.426
Statins581 (437–724)889 (807–971)< 0.001< 0.001681 (457–904)639 (511–767)0.2030.641
Digoxin890 (801–998)691 (567–816)0.0040.519652 (531–774)626 (457–795)0.0370.095
  1. *Relationship of drugs with survival time was bivariately evaluated with Kaplan-Meier analysis; **relationship of drugs with mortality rate was multivariately adjusted by age, gender, body mass index, CAD, CHF, atrial fibrillation, hypertension, heart rate, systolic blood pressure, diastolic blood pressure, hemoglobin, albumin, glomerular filtration rate, fasting plasma glucose, triglyceride, low density lipoprotein cholesterol and high density lipoprotein cholesterol using Cox Regression
  2. Abbreviations: ACEI/ARBs Renin-angiotensin-aldosterone system inhibitors/angiotensin receptor blockers, CAD Coronary artery disease, CHF Chronic heart failure, GFR Glomerular filtration rate