Types of severe adverse effects | N (%) |
---|---|
Non-neurological SAE (N = 314) | |
Asthenia | 65 (20.7) |
Vertigos | 20 (6.4) |
Itching | 15 (4.8) |
Localised or generalised oedema | 9 (2.9) |
Severe headache | 235 (74.8) |
Myalgia | 201 (64.0) |
Diarrhoea + vomiting | 88 (28.0) |
Arthralgia | 197 (62.7) |
Neurological SAE (N = 631) | |
Coma | 594 (94.1) |
Paralysis | 13 (2.1) |
Palpebral SCH | 245 (38.8) |
Speech disabilities | 188 (29.8) |
Motor deficit | 476 (75.4) |