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Table 3 Characteristics of study population from identified clusters in comparison to those from the remainder regions of NSW

From: Adverse drug reactions due to opioid analgesic use in New South Wales, Australia: a spatial-temporal analysis

 

2004–05 to 2008–09

2009–10 to 2013–14

Clusters

n (%)

Non-clusters

n (%)

X2 p-value

Clusters

n (%)

Non-clusters

n (%)

X2 p-value

Total

3255 (100)

5148 (100)

 

7493 (100)

10,880 (100)

 

Age group (years)

  < 18

77 (2.4)

141 (2.7)

0.005

161 (2.1)

235 (2.2)

0.396

 18–44

509 (15.6)

820 (15.9)

 

1098 (14.7)

1585 (14.6)

 

 45–64

625 (19.2)

1073 (20.8)

 

1403 (18.7)

2247 (20.7)

 

 65–84

1404 (43.1)

2263 (44.0)

 

3252 (43.4)

4469 (41.1)

 

 85+

640 (19.7)

851 (16.5)

 

1579 (21.1)

2344 (21.5)

 

Gender

 Male

1401 (43.0)

2032 (39.5)

0.001

3006 (40.1)

4450 (40.9)

0.288

 Female

1854 (57.0)

3116 (60.5)

 

4487 (59.9)

6430 (59.1)

 

Marital status

 Single

1605 (49.3)

2616 (50.8)

0.178

3946 (52.7)

5659 (52.0)

0.386

 Others

1650 (50.7)

2532 (49.2)

 

3547 (47.3)

5221 (48.0)

 

Private insurance

 Yes

1043 (32.0)

1269 (24.7)

< 0.001

1941 (25.9)

3501 (32.2)

< 0.001

 No

2212 (68.0)

3879 (75.3)

 

5552 (74.1)

7379 (67.8)

 

Socioeconomic disadvantage

 1st (most)

589 (18.1)

1255 (24.4)

< 0.001

2008 (26.8)

2114 (19.4)

< 0.001

 2nd

639 (19.6)

1114 (21.6)

 

1897 (25.3)

2050 (18.8)

 

 3rd

609 (18.7)

997 (19.4)

 

1675 (22.4)

2092 (19.2)

 

 4th

660 (20.3)

963 (18.7)

 

1385 (18.5)

1955 (18.0)

 

 5th (least)

758 (23.3)

819 (15.9)

 

528 (7.0)

2669 (24.5)

 

Rurality of residence

 Urban

3245 (99.7)

4649 (90.3)

<.0001

7251 (96.8)

10,137 (93.2)

< 0.001

 Rural

10 (0.3)

499 (9.7)

 

242 (3.2)

743 (6.8)

 

Convenient access to pharmacy

 More

3115 (95.7)

4399 (85.5)

< 0.001

6752 (90.1)

9821 (90.3)

0.727

 Less

140 (4.3)

749 (14.5)

 

741 (9.9)

1059 (9.7)

 

Disposition status

 Death

196 (6.0)

196 (3.8)

< 0.001

276 (3.7)

373 (3.4)

0.357

 Alive

3059 (94.0)

4952 (96.2)

 

7217 (96.3)

10,507 (96.6)

 

Severity of comorbidities

 Minor

1760 (54.1)

3023 (58.7)

0.005

4467 (59.6)

6585 (60.5)

0.995

 Moderate

744 (22.9)

1073 (20.8)

 

1723 (23.0)

2305 (21.2)

 

 Severe

751 (23.1)

1052 (20.4)

 

1303 (17.4)

1990 (18.3)

 

Clinical conditionsa

 CHD

282 (8.7)

381 (7.4)

0.037

281 (3.8)

396 (3.6)

0.696

 Cancer

578 (17.8)

795 (15.4)

0.005

983 (13.1)

1566 (14.4)

0.014

 BDD

199 (6.1)

211 (4.1)

< 0.001

373 (5.0)

379 (3.5)

< 0.001

 COPD

234 (7.2)

326 (6.3)

0.125

421 (5.6)

511 (4.7)

0.005

 CVD

96 (2.9)

128 (2.5)

0.199

140 (1.9)

208 (1.9)

0.832

 Diabetes

454 (13.9)

685 (13.3)

0.402

950 (12.7)

1402 (12.9)

0.679

 Osteoarthritis

147 (4.5)

201 (3.9)

0.170

187 (2.5)

279 (2.6)

0.771

Number of mental disorders

 None

2436 (74.8)

4115 (79.9)

< 0.001

5467 (73.0)

8346 (76.7)

< 0.001

 Single

674 (20.7)

869 (16.9)

 

1699 (22.7)

2232 (20.5)

 

 Multiple (≥2)

145 (4.5)

164 (3.2)

 

327 (4.4)

302 (2.8)

 
  1. aSelected clinical conditions including coronary heart diseases (CHD), cancer, brain degenerative disorders (BDD), chronic obstructive respiratory diseases (COPD), cerebrovascular diseases (CVD), diabetes, and osteoarthritis, were compared between those with and without a condition, respectively