Fig. 5

Anti-nociceptive activities of poncirin in thermal hyperalgesia and cold allodynia induced by CFA (a) inhibition of acute thermal hyperalgesia, (b) inhibition of chronic thermal hyperalgesia and (c) inhibition of cold allodynia. Each data point represents the mean ± SEM of 6–7 mice per group. *p < 0.05, **p < 0.01 and ***p < 0.001 denote the significant differences from the negative control group