Fig. 3
From: In vitro toxic evaluation of two gliptins and their main impurities of synthesis
Production of reactive oxygen (ROS) and nitrogen (RNS) species in 3 T3 cells 24 h after incubation with DCFH-DA: a sitagliptin – STG and its impurities S1 and S2, b vildagliptin – VLG and its impurities V1 and V2. Results are expressed as mean ± standard error of the mean. Statistical analysis performed through ANOVA/Bonferroni (*p < 0.05; **p < 0.01; ***p < 0.001 versus control)