Skip to main content

Table 1 Toxicity risk prediction for the γ-hexalactone from the computer simulation

From: Gamma-hexalactone flavoring causes DNA lesion and modulates cytokines secretion at non-cytotoxic concentrations

ID substanceToxic risk by admetSAR 1; Osiris Property Explorer 2, pkCSM 3; PreADMET 4;
MutagenicCarcinogenic*
γ-hexalactoneNot Detected 1
Not Detected 2
Not Detected 3
Yes 4
Not Detected 1
Not Detected 2
Yes 4
  1. The toxic risks assessed, mutagenicity and carcinogenicity side effects were interpreted and expressed as “Yes” or “No” and “Not Detected” risk. *The pkCSM platform does not evaluate the carcinogenicity parameter. The superscripted numbers identify the platform used in the predictions