Fig. 9

Pre-pulse inhibition is disordered in ketamine treated rats; retained in KEA-1010. Ketamine and KEA-1037, but not KEA-1010, induced pre-pulse inhibition at 5 minutes following drug administration (a), amplitude (b). No difference in percent pre-pulse inhibition was observed at 30 min following drug administration (c), amplitude (d). Data mean (SEM). *p < 0.05 (test vs. saline); ** p < 0.01 (test vs. saline); #p < 0.05 (test vs. ketamine); ## p < 0.01 test vs. ketamine; Students T test); ### p < 0.001 (test vs. ketamine; Students T test). N = 8 all groups