Fig. 5From: SBF-1 inhibits contact hypersensitivity in mice through down-regulation of T-cell-mediated responsesSchematic representation mechanism of SBF-1’s effects on T cells. SBF-1 suppresses T-cell-mediated immune responses in vitro and in vivo by inhibiting T cell proliferation, activation, cytokine production and inducing apoptosis, which is closely related to its blockage of AKT signaling pathwaysBack to article page