Fig. 5
From: SBF-1 inhibits contact hypersensitivity in mice through down-regulation of T-cell-mediated responses
Schematic representation mechanism of SBF-1’s effects on T cells. SBF-1 suppresses T-cell-mediated immune responses in vitro and in vivo by inhibiting T cell proliferation, activation, cytokine production and inducing apoptosis, which is closely related to its blockage of AKT signaling pathways