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Table 1 Effect of different concentrations of flubendiamide and copper on per cent viability of rat splenocytes following their in vitro exposure to these xenobiotics

From: In vitro and in vivo effects of flubendiamide and copper on cyto-genotoxicity, oxidative stress and spleen histology of rats and its modulation by resveratrol, catechin, curcumin and α-tocopherol

Treatment% Dead Splenocytes
Control4.93 ± 0.67
Vehicle control (DMSO) 50 μl7.46 ± 0.83
1.0 μM Flubendiamide12.98 ± 1.92
2.5 μM Flubendiamide15.13 ± 1.87
5.0 μM Flubendiamide22.18 ± 1.67
7.5 μM Flubendiamide24.28 ± 2.24
10 μM Flubendiamide28.09 ± 1.33
15 μM Flubendiamide29.76 ± 1.55
20 μM Flubendiamide32.32 ± 1.32
40 μM Flubendiamide45.42 ± 2.50
60 μM Flubendiamide67.89 ± 3.14
80 μM Flubendiamide88.81 ± 5.62
1.0 μM Copper6.45 ± 3.04
2.5 μM Copper10.34 ± 1.63
5.0 μM Copper13.88 ± 1.39
7.5 μM Copper16.66 ± 1.92
10 μM Copper26.08 ± 4.73
15 μM Copper28.39 ± 1.74
20 μM Copper34.95 ± 5.87
40 μM Copper51.09 ± 2.01
60 μM Copper61.11 ± 2.03
80 μM Copper76.68 ± 1.71
  1. Data presented are Mean ± SEM of three observations