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Table 2 The Intra- and Inter-day precision and accuracy (n = 6), extraction recovery (n = 6) for parecoxib, valdecoxib and celecoxib (IS) in rat plasma

From: Determination of parecoxib and valdecoxib in rat plasma by UPLC-MS/MS and its application to pharmacokinetics studies

CompoundConcentration (ng/mL)Intra-dayInter-dayRecovery
Precision (RSD%)Accuracy (RE%)Precision (RSD%)Accuracy (RE%)Mean + SD (%)RSD (%)
 1008.34.311.510.587.0 ± 1.82
Parecoxib80010.5−3.213.96.679.0 ± 5.06.4
 80005.6611.4−787.1 ± 0.40.5
 59.55.614−5.6114.6 ± 8.47.3
Valdecoxib407.31.27.114.879.3 ± 1.11.4
 4004.92.97.56.470.0 ± 1.42.0
Celecoxib2003.87.34.8879.5 ± 2.02.6