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Fig. 2 | BMC Pharmacology and Toxicology

Fig. 2

From: Inhibition of PI3K/AKT molecular pathway mediated by membrane estrogen receptor GPER accounts for cryptotanshinone induced antiproliferative effect on breast cancer SKBR-3 cells

Fig. 2

CPT inhibits SKBR-3 cell viability via GPER mediated pathway. a GPER expression in GPER siRNA transfected SKBR-3 cells were tested by Western blot with non-siRNA transfection as control. **P < 0.01 vs control group. b Viability of GPER knocked down SKBR-3 cells was tested by MTT viability assay. The results are means of three independent replicates ± S.D. **P < 0.01 vs control group or △△P < 0.01 vs non-siRNA group were considered as statistically significant. c Viability of SKBR-3 cells treated by CPT with G1 or G15 was tested by MTT viability assay. The results are means of three independent replicates ± S.D. **P < 0.01 vs control group or △△P < 0.01 vs 5 μM CPT treated group were considered as statistically significant

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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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