Table 3 Demographic characteristics of subjects enrolled in the study
15 mg BID (n = 3) | 10 mg BID (n = 9) | 20 mg QD (n = 8) | 15 mg QD (n = 7) | 10 mg QD (n = 12) | Total (n = 39) | P | ||
|---|---|---|---|---|---|---|---|---|
Demographic characteristics | Age | 50.0 ± 3.0 | 56.4 ± 13.3 | 49.1 ± 17.6 | 60.9 ± 10.5 | 63.4 ± 14.6 | 56.9 ± 14.8 | 0.147 |
BMI (kg/m2) | 26.1 ± 2.3 | 23.7 ± 2.5 | 23.2 ± 3.8 | 26.6 ± 4.4 | 22.9 ± 2.4 | 23.9 ± 3.3 | 0.126 | |
CrCl (mL•min−1) | 110.4 ± 31.5 | 100.6 ± 27.5 | 91.9 ± 35.1 | 84.4 ± 20.1 | 76.6 ± 34.2 | 89.6 ± 31.5 | 0.334 | |
ALT (U•L−1) | 18.7 ± 3.5 | 17.0 ± 8.2 | 30.4 ± 12.8 | 23.8 ± 16.4 | 18.7 ± 12.1 | 22.1 ± 12.5 | 0.092 | |
Alb (g•L−1) | 43.7 ± 6.7 | 39.9 ± 5.1 | 42.2 ± 6.4 | 39.7 ± 5.9 | 41.8 ± 4.0 | 41.3 ± 5.2 | 0.694 | |