Table 5 Recommended doses of antiviral drugs for different renal impairments
Antiviral drugs | Creatinine clearance rate (mL/min) | Hemodialysis | ||
|---|---|---|---|---|
≥50 | 30–49 | 10–29 | ||
Lamivudine | 100 mg qd | – | – | – |
Adefovir Dipivoxil | 10 mg qd | 10 mg/48 h (20–49) | 10 mg/72 h (10–19) | 10 mg/7 days |
Entecavir | 1 mg qd | 0.5 mg qd | 0.3 mg qd or 0.5 mg/48 h | 0.1 mg qd or 0.5 mg/72 h |
Tenofovir Disoproxil Fumarate | 300 mg qd | 300 mg/48 h | 300 mg/(72-96 h) | 300 mg/7 days |
Telbivudine | 600 mg qd | 600 mg/48 h | 600 mg/72 h | 600 mg/96 h |