Skip to main content
Fig. 5 | BMC Pharmacology and Toxicology

Fig. 5

From: Brown adipose tissue activity is modulated in olanzapine-treated young rats by simvastatin

Fig. 5

Effects of olanzapine, simvastatin treatment and simvastatin treatment combined with olanzapine on hepatic lipid levels. Hepatic mRNA expression of cholesterol biosynthesis and fatty acid synthesis-related genes: Srebp2 (a), Hmgcr (b), Hmgcs (c), Srebp1(d), Fasn (e) and Acc1 (f). g Lipid level of liver. The data from ORO staining. h Representative images of randomly selected sections of the liver stained for Oil red O in rats. Scale bars, 100 μm. Values are means ± SEM. *p < 0.05; **p < 0.01 vs. control; #p < 0.05, ##p < 0.01 vs. olanzapine-only group

Back to article page