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Fig. 2 | BMC Pharmacology and Toxicology

Fig. 2

From: Clinical characteristics and time trends of hospitalized methadone exposures in the United States based on the Toxicology Investigators Consortium (ToxIC) case registry: 2010–2017

Fig. 2

The percent of all methadone cases/total cases to the ToxIC Registry by year. Frequency distribution of methadone poisoning cases in 2015 had a significant difference with years of 2011, 2012, 2013, 2014 (p < 0.001). Frequency distribution of methadone poisoning cases in 2017 had a significant difference with years of 2011, 2012, 2013, 2014 (p < 0.001). Frequency distribution of methadone poisoning cases in the 2010 as well as 2016 had a significant difference with years of 2011, 2012, 2013, 2014 (p < 0.001).

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