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Table 1 Effect of curcumin on the levels of MDA, GSH, SOD and GSH-Px in cerebral homogenates prepared from ACR intoxicated rats (n = 10, mean ± SD)

From: The anti-apoptotic, antioxidant and anti-inflammatory effects of curcumin on acrylamide-induced neurotoxicity in rats

Groups MDA
(nmol/mg prot)
GSH
(mg/g prot)
SOD
(U/mg prot)
GSH-Px
(U/mg prot)
Normal 0.425 ± 0.141 4.41 ± 0.58 60.21 ± 5.38 14.81 ± 1.95
ACR 1.133 ± 0.352 ** 2.30 ± 0.47** 52.72 ± 6.94 ** 10.36 ± 1.84 **
ACR + curcumin 50 mg/kg 0.918 ± 0.322 2.77 ± 0.46 # 53.89 ± 8.02 12.58 ± 1.96 #
ACR + curcumin 100 mg/kg 0.854 ± 0.216 # 2.92 ± 0.59 # 59.16 ± 6.46 # 13.15 ± 1.87 ##
  1. **P < 0.01 compared to the corresponding control rats. # P < 0.05, ## P < 0.01; compared with the corresponding ACR group