Table 3 Studies of the prevalence of potential DDIs in included articles
Region | Author | Pathology | Target population | Study setting | No. of patients | No. of patients with DDIs | Prevalence patients with DDIs (%) | No. of potential DDIs | |||
|---|---|---|---|---|---|---|---|---|---|---|---|
Major | Moderate | Minor | Unknown& Contraindication | ||||||||
Oromia | Gunasekaran et al., 2016 [25] | All | All hospitalized patients | All wards | 300 | 267 | 89.00 | 62 (23.2%) | 95 (35.58%) | 110 (41.2%) | Â |
Behailu Terefe Tesfaye et al., 2017 [6] | HIV/AIDS | All HIV infected patients | ART Clinic | 350 | 350 | 100.00 | 2 (0.08%) | 1767 (72.69%) | 662 (27.2%) | Â | |
Diksis et al., 2019 [5] | Cardiac disorder | Cardiac adult patients | Medical ward | 200 | 195 | 97.50 | 316 (32.7%) | 441 (45.6%) | 210 (21.7%) | Â | |
Chelkeba L et al., 2013 [26] | Cardiac disorder | Patients on CV medication in OPD | Cardiac clinic | 322 | 297 | 92.24 | 88 (29.6%) | 200 (67.34%) | 9 (3.03%) | Â | |
Amhara | B.Akshaya Srikanth et al., 2014 [27] | All | All hospitalized patients | Medical ward | 100 | 78 | 78.00 | 53 (12.8%) | 253 (61.26%) | 107 (25.9%) | Â |
Admassie, et al., 2013 [28] | All | All hospitalized patients | Inpatients and Out patient | 2180 | 711 | 32.61 | 127 (9.59%) | 1020 (77.04%) | 177 (13.4%) | Contraindication = 11 (0.83%) | |
Henok Getachew et al., 2016 [29] | All | All hospitalized pediatric patients | Pediatric ward | 384 | 176 | 45.83 | 40 (10.2%) | 201 (51.15%) | 152 (38.7%) | Â | |
Tigray | Teka et al., 2016 [30] | All | All hospitalized elder patients | Medical ward | 140 | 87 | 62.14 | 46 (51.6%) | 36 (43.9%) | 0 (0.0%) | Contraindication = 5 (6.1%) |
Zeru Gebretsadik et al., 2017 [31] | All | All patients who come for medical service | Outpatient pharmacy | 596 | 275 | 46.14 | 34 (110.3%) | 210 (63.444%) | 87 (26.3%) | unknown = 22 (6.65%) | |
Haftay Berhane Mezgebe, 2015 [7] | Psychiatric illness | Patients with psychiatric illness | Psychiatric unit | 216 | 176 | 81.48 | 198 (43.8%) | 232 (51.33%) | 22 (4.87%) | Contraindication = 13 (2.88%) | |
Teklay et al., 2014 [32] | DVT | Patients on warfarin therapy | Medical ward | 133 | 132 | 99.25 | 11,827.6(%) | 310 (72.43%) | 0 (0.00%) | Â | |
Yesuf TA, et al., 2017 [33] | All | All hospitalized patients | Medical ward | 204 | 135 | 53.43 | 150 (80.6%) | 36 (19.35%) | 0 (0.00%) | Contraindication = 80 (43%) | |
Addis Ababa | Tesfaye and Nedi, 2017 [34] | All | All hospitalized patients | Medical ward | 252 | 197 | 78.17 | 94 (13.1%) | 385 (53.55%) | 240 (33.4%) | Â |
Kibrom et al., 2018 [35] | All | Adult patients | Medical ward | 384 | 209 | 54.43 | 105 (35.7%) | 157 (53.4%) | 32 (10.9%) | Contraindication = 2 (0.68%) | |