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Table 6 Robust generalized linear regression models

From: Broad Spectrum epidemiological contribution of cannabis and other substances to the teratological profile of northern New South Wales: geospatial and causal inference analysis

Parameter Estimate (95%C.I.) P-Value
PC1
 Cannabis 3.46 (0.58, 6.34) 0.0382
 Cigarettes: Alcohol 0.45 (0.04, 0.85) 0.0521
 Cigarettes −1.52 (−2.89, − 0.16) 0.0510
 Alcohol: Cannabis −1 (−1.82, − 0.17) 0.0369
PC1 as Arcsinh
 Cannabis 2.89 (0.87, 4.92) 0.0172
 Cigarettes: Alcohol 0.39 (0.11, 0.67) 0.0212
 Cigarettes −1.31 (−2.26, − 0.36) 0.0204
 Alcohol: Cannabis −0.85 (− 1.43, − 0.26) 0.0162
Central Nervous System
 Anencephalus
  Cigarettes: Cannabis 0.1 (0.04, 0.16) 0.0065
  Cigarettes: Alcohol 0.55 (0.1, 1) 0.0384
  Cigarettes −1.81 (−3.32, − 0.31) 0.0399
  Cigarettes: Alcohol: Cannabis −0.03 (− 0.05, − 0.01) 0.0068
 CNO
  Alcohol 2.8 (0.84, 4.76) 0.0189
  Cannabis 2.6 (1.06, 4.14) 0.0078
  Cigarettes: Alcohol: Cannabis 0.02 (0.01, 0.04) 0.0156
  Cigarettes: Cannabis −0.08 (− 0.14, − 0.02) 0.0194
  Alcohol: Cannabis − 0.79 (−1.25, − 0.34) 0.0067
Cardiovascular System
 ASD
  Cigarettes: Alcohol: Cannabis 0.12 (0.06, 0.18) 0.0051
  Cannabis 8.4 (3.93, 12.88) 0.0062
  Alcohol 21.3 (8.16, 34.43) 0.0130
  Cigarettes 3.48 (1.07, 5.89) 0.0223
  Cigarettes: Alcohol −1.05 (− 1.78, −0.32) 0.0227
  Alcohol: Cannabis −2.5 (−3.8, −1.19) 0.0056
  Cigarettes: Cannabis −0.4 (− 0.61, − 0.19) 0.0055
 VSD
  Cigarettes: Alcohol: Cannabis 0.04 (0.01, 0.07) 0.0242
  Cannabis 3.38 (0.63, 6.13) 0.0366
  Alcohol: Cannabis −0.98 (−1.79, − 0.18) 0.0381
  Cigarettes: Cannabis −0.13 (− 0.23, − 0.03) 0.0239
 PDA
  Cannabis 6.68 (1.28, 12.07) 0.0416
  Cigarettes: Alcohol: Cannabis 0.09 (0.01, 0.16) 0.0504
  Alcohol 16.71 (0.91, 32.5) 0.0719
  Cigarettes: Cannabis −0.29 (− 0.53, − 0.04) 0.0536
  Alcohol: Cannabis −1.98 (−3.55, − 0.4) 0.0392
 Tetralogy Fallot
  Cannabis 0.08 (0.01, 0.15) 0.0410
Gastrointestinal System
 Cigarettes: Alcohol: Cannabis 0.02 (0.01, 0.03) 0.0031
 Cigarettes 0.7 (0.27, 1.13) 0.0090
 Cigarettes: Alcohol −0.22 (−0.35, − 0.09) 0.0081
 Cigarettes: Cannabis −0.07 (− 0.11, − 0.04) 0.0029
 Small Intestinal Stenosis or Atresia - Additive
  Cannabis 0.043 (0.004, 0.081) 0.0463
  Small Intestinal Stenosis or Atresia - IR   
  Cigarettes: Cannabis 0.002 (0, 0.005) 0.0692
Genitourinary System
 Cigarettes: Alcohol: Cannabis 0.01 (0, 0.01) 0.0113
 Cigarettes 0.28 (0.08, 0.48) 0.0199
 Cigarettes: Alcohol −0.09 (− 0.15, − 0.02) 0.0195
 Cigarettes: Cannabis − 0.03 (− 0.04, − 0.01) 0.0103
 Renal Pelvis Obstruction
  Alcohol: Cannabis 0.65 (0.1, 1.21) 0.0425
  Cigarettes: Cannabis 0.08 (0, 0.15) 0.0656
  Cigarettes: Alcohol: Cannabis −0.02 (− 0.04, 0) 0.0614
  Cannabis −2.17 (−4.03, − 0.31) 0.0450
Chromosomal Anomalies
 Alcohol: Cannabis 0.02 (0, 0.05) 0.0678
 Alcohol −0.82 (−1.62, − 0.02) 0.0684
 GIT
  Cigarettes: Cannabis 0.04 (0.01, 0.08) 0.0380
  Cigarettes: Alcohol 0.34 (−0.01, 0.68) 0.0878
  Cigarettes −1.07 (−2.17, 0.02) 0.0862
  Cigarettes: Alcohol: Cannabis −0.01 (− 0.03, 0) 0.0357
 Respiratory
  Cigarettes: Cannabis 0.01 (0, 0.02) 0.0927
  Cigarettes: Alcohol: Cannabis 0 (−0.01, 0) 0.0497
 Downs - Additive
  Cannabis 0.04 (0.01, 0.07) 0.0186
  Alcohol −1.29 (−2.43, − 0.15) 0.0464
 Downs - Interactive
  Cigarettes 0.21 (0.01, 0.41) 0.0599
  Cigarettes: Alcohol −0.07 (− 0.13, − 0.01) 0.0441
  Cigarettes: Alcohol: Cannabis 0.0007 (0.0002, 0.0013) 0.0198
Body Wall
 Musculoskeletal
  Cannabis 2.71 (0.93, 4.49) 0.0123
  Cigarettes: Cannabis −0.13 (− 0.22, − 0.05) 0.0113
  Alcohol: Cannabis − 0.8 (−1.32, − 0.27) 0.0130
  Cigarettes: Alcohol: Cannabis 0.04 (0.01, 0.06) 0.0118
 Gastroschisis
  Cigarettes 0.11 (0, 0.21) 0.0684
  Cannabis 0.27 (0, 0.53) 0.0705
  Cigarettes: Cannabis −0.01 (−0.02, 0) 0.0920
 Exomphalos
  Cigarettes: Cannabis 0.1 (0.04, 0.16) 0.0118
  Cannabis 0.56 (0.14, 0.98) 0.0289
  Cigarettes: Alcohol 1.03 (0.21, 1.85) 0.0357
  Alcohol −12.72 (−24.65, −0.8) 0.0661
  Cigarettes −3.2 (−5.78, − 0.61) 0.0386
  Cigarettes: Alcohol: Cannabis −0.04 (− 0.06, − 0.02) 0.0093
Face
 Cleft Palate / Lip
  Cannabis 0.57 (0.22, 0.92) 0.0092
  Cigarettes: Alcohol 0.04 (0, 0.07) 0.0467
  Alcohol: Cannabis −0.12 (−0.2, − 0.04) 0.0128