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Fig. 2 | BMC Pharmacology and Toxicology

Fig. 2

From: Attenuation of LPS-induced acute lung injury by continentalic acid in rodents through inhibition of inflammatory mediators correlates with increased Nrf2 protein expression

Fig. 2

Effect of treatment with continentalic acid (10, 50 and 100 mg/kg) on levels of antioxidant enzymes such as (a) GSH, (b) GST, (c) Catalase, (d) SOD, (e) MDA in LPS-induced lung tissue. The level of these antioxidants and oxidative stress parameters were markedly compromised. However, continentalic acid post treatment significantly enhanced antioxidant enzymes such as GSH, GST, Catalase, SOD and reduced the level of MDA. The results were shown in percentage. All data were expressed as mean (n = 8) ± SD. ###p < 0.001 compared to control group; *p < 0.05, **p < 0.01 and ***p < 0.001 compared to LPS-treated group

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