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Fig. 2 | BMC Pharmacology and Toxicology

Fig. 2

From: Nebivolol combined with tetrahydrobiopterin affects diastolic function in spontaneously hypertensive rats via the nitric oxide/cyclic guanosine monophosphate signalling pathway

Fig. 2

Application of HPLC to determine the content of BH4 and BH4/BH2 inmyocardium. a The content of BH4 in myocardium, BH4 treatment significantly increased myocardial BH4. b BH4/BH2 in myocardium, although nebivolol monotherapy did not improve myocardium BH4/BH2 ratio,but nebivolol combined with BH4 treatment significantly increased the BH4/BH2 ratio. *P < 0.01 versus Control, # p < 0.01 versus L-N&L-BH4

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