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Table 1 Baseline demographics and characteristics of the study population

From: Common causes and characteristics of adverse drug reactions in older adults: a retrospective study

 

Total (N = 14,864)

< 65 years (N = 11,427)

≥ 65 years (N = 3437)

P value

 

18,842

14,690 (78.0)

4152 (22.0)

 

Age

49.5 ± 19.2

42.4 ± 15.2

74.6 ± 7.2

< 0.001*

Female

10,897 (57.8)

8496 (57.8)

2401 (57.8)

0.993†

Causality

 Certain

2879 (15.3)

2533 (17.2)

346 (8.3)

< 0.001†

 Probable

15,963 (84.7)

12,157 (82.8)

3806 (91.7)

< 0.001†

Severity

 Grade 1

1243 (6.6)

957 (6.5)

286 (6.9)

0.392†

 Grade 2

16,606 (88.1)

13,013 (88.6)

3593 (86.5)

< 0.001†

 Grade 3

981 (5.2)

714 (4.9)

267 (6.4)

< 0.001†

 Grade 4

9 (0.0)

6 (0.0)

3 (0.1)

0.423‡

 Grade 5

3 (0.0)

0 (0.0)

3 (0.1)

0.011‡

  1. Values represent numbers of cases with percentage in parentheses. Plus-minus values are means ± standard deviations. P values were calculated using *Student’s t-test, † the chi-square test, and ‡ Fisher’s exact test