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Table 3 Laboratory safety assessments evaluated at screening and post-study

From: Pharmacokinetic study of a novel oral formulation of S-adenosylmethionine (MSI-195) in healthy subjects: dose escalation, food effect and comparison to a commercial nutritional supplement product

General Biochemistry

Sodium, potassium, chloride, glucose, urea (BUN), creatinine, total bilirubin, alkaline phosphatase, AST, ALT, albumin

Endocrinology

Vitamin B12 and folic acid

Hematology

White cell, red cell, hemoglobin, hematocrit, MCV, MCH, MCHC, RDW, platelets, MPV, neutrophil, lymphocyte, monocyte, eosinophil and basophil

Urinalysis

Color, appearance, specific gravity, pH, leukocyte, protein, glucose, ketones, bilirubin, blood, nitrite, urobilinogen

Microscopic examination only performed if dipstick test is positive for leukocyte, blood, nitrite or protein

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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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