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Fig. 3 | BMC Pharmacology and Toxicology

Fig. 3

From: Improved effect of a mitochondria-targeted antioxidant on hydrogen peroxide-induced oxidative stress in human retinal pigment epithelium cells

Fig. 3

TPP-Niacin improved H2O2-induced decreasing antioxidant status in ARPE-19 cells, which were pre-treated with TPP-Niacin at 25 and 50 μM for 2 h and then treated with H2O2 (300 μM) for 24 h. The levels of SOD1 (a), SOD2 (b) Catalase, (c) and GPx activity (d) were measured to assess the levels of antioxidant activities. ## P < 0.01, ### P < 0.001 versus control group and **P < 0.01, ***P < 0.001 versus the H2O2-treated group were considered statistically significant differences. SOD1 and 2: superoxide dismutase 1 and 2, and GPx: glutathione peroxidase

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