Table 2 Summary of reported adverse events by dose
2-Hydroxybenzylamine acetate dose | Total (n = 18) | |||
|---|---|---|---|---|
Placebo (n = 6) | 500 mg (n = 6) | 750 mg (n = 6) | ||
Any event, n (%) | 4 (67) | 6 (100) | 4 (67) | 14 (78) |
Headache | 2 (33) | 2 (33) | 2 (33) | 6 (33) |
GI distress (nausea, bloating, constipation) | 2 (33) | 1 (17) | 0 (0) | 3 (17) |
Rash/itching | 1 (17) | 1 (17) | 1 (17) | 3 (17) |
Urine odor | 0 (0) | 2 (33) | 0 (0) | 2 (11) |
Dry mouth | 1 (17) | 1 (17) | 0 (0) | 2 (11) |
Nasal congestion | 0 (0) | 2 (33) | 0 (0) | 2 (11) |
Lethargy/sleepiness | 0 (0) | 1 (17) | 1 (17) | 2 (11) |
Hypertension | 0 (0) | 1 (17) | 0 (0) | 1 (6) |
Eye irritation | 0 (0) | 1 (17) | 0 (0) | 1 (6) |