Table 3 Factors associated to transient renal toxicity at univariable analysis
From: Risk factors for renal toxicity after inpatient cisplatin administration
N (%) | p-value | |
|---|---|---|
Sex | ||
Male | 42 (40) | 0.91 |
Female | 32 (42) | |
Smoke | ||
No | 33 (42) | 0.81 |
Yes | 26 (41) | |
Former Smokers | 12 (36) | |
Alcohol abuse | ||
No | 58 (38) | 0.02 |
Yes | 16 (61) | |
Diuretics | ||
No | 36 (34) | 0.14 |
During Cisplatin | 32 (48) | |
Before or after Cisplatin | 6 (54) | |
ACE Inhibitor | ||
No | 68 (40) | 0.70 |
Yes | 6 (46) | |
Metformin | ||
No | 70 (40) | 0.07 |
Yes | 4 (80) | |
ICM | ||
No | 65 (42) | 0.46 |
Yes | 9 (35) | |
Obesity | ||
No | 8 (38) | 0.07 |
Yes | 6 (75) | |
Diabete | ||
No | 68 (40) | 0.21 |
Yes | 6 (60) | |
Dyslipidemia | ||
No | 63 (40) | 0.26 |
Yes | 11 (52) | |
Cardiopathy | ||
No | 70 (41) | 0.57 |
Yes | 4 (33) | |
Vasculopathy | ||
No | 68 (42) | 0.37 |
Yes | 6 (32) | |
COPD | ||
No | 65 (40) | 0.55 |
Yes | 9 (47) | |
Hypertension | ||
No | 45 (35) | 0.017 |
Yes | 29 (54) | |
Cirrhosis | ||
No | 70 (40) | 0.015 |
Yes | 4 (100) | |
Hypoalbuminemia | ||
No | 49 (45) | 0.40 |
Yes | 10 (55) | |
Mannitol | ||
No | 49 (43) | 0.92 |
Yes | 23 (42) | |
NSAID | ||
No | 58 (38) | 0.06 |
Yes | 16 (61) | |
Number of cycles < 4 | ||
No | 19 (27) | 0.002 |
Yes | 55 (50) | |