Fig. 4
From: Proposal of initial and maintenance dosing regimens with linezolid for renal impairment patients
Boxplots of Cmin after dose reduction to 300 mg every 12 h in the RI and non-RI groups. For each boxplot, the horizontal line across the box within each box represents the median, each box represents the range between the 25th and 75th percentiles, the two whiskers represent the minimum and maximum values that are within 1.5 × IQR, and points beyond the whiskers represent outliers. Open circles represent Cmin < 2.0 mg/L, closed circles represent Cmin within the desired range of 2–8 mg/L, and open square represent Cmin values of overexposure (> 8 mg/L). Abbreviations: Cmin, trough concentration; RI, renal impairment